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Article Publish Status: FREE
Abstract Title:

Fructans as Immunomodulatory and Antiviral Agents: The Case of.

Abstract Source:

Biomolecules. 2019 Oct 16 ;9(10). Epub 2019 Oct 16. PMID: 31623122

Abstract Author(s):

Erin Dobrange, Darin Peshev, Bianke Loedolff, Wim Van den Ende

Article Affiliation:

Erin Dobrange

Abstract:

Throughout history, medicinal purposes of plants have been studied, documented, and acknowledged as an integral part of human healthcare systems. The development of modern medicine still relies largely on this historical knowledge of the use and preparation of plants and their extracts. Further research into the human microbiome highlights the interaction between immunomodulatory responses and plant-derived, prebiotic compounds. One such group of compounds includes the inulin-type fructans (ITFs), which may also act as signaling molecules and antioxidants. These multifunctional compounds occur in a small proportion of plants, many of which have recognized medicinal properties.is a well-known medicinal plant and products derived from it are sold globally for its cold- and flu-preventative and general health-promoting properties. Despite the well-documented phytochemical profile ofplants and products, little research has looked into the possible role of ITFs in these products. This review aims to highlight the occurrence of ITFs inderived formulations and the potential role they play in immunomodulation.

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