Abstract Title:

Antihyperglycemic activity of phenolics from Pterocarpus marsupium.

Abstract Source:

J Nat Prod. 1997 Jun;60(6):609-10. PMID: 9214733

Abstract Author(s):

M Manickam, M Ramanathan, M A Jahromi, J P Chansouria, A B Ray

Article Affiliation:

Department of Medicinal Chemistry, Banaras Hindu University, Varanasi, India.

Abstract:

Glucose levels in rats with hyperglycemia induced by streptozotocin were determined after i.p. administration of marsupsin (1), pterosupin (2), and pterostilbene (3), three important phenolic constituents of the heartwood of Pterocarpus marsupium. Marsupsin and pterostilbene significantly lowered the blood glucose level of hyperglycemic rats, and the effect was comparable to that of 1,1-dimethylbiguanide (metformin).

Study Type : Animal Study

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