A positive association was found between vitamin D deficiency and dry eye on comparing the above parameters. - GreenMedInfo Summary
A study of the association between Vitamin D deficiency and Dry Eye Syndrome (DES) in the Indian population.
Indian J Ophthalmol. 2022 Feb ;70(2):500-504. PMID: 35086225
Nikita Jain
Purpose: A study of the association between vitamin D deficiency and dry eye syndrome (DES) in the Indian population.
Methods: This was a cross-sectional, hospital-based observational study. Sixty patients diagnosed with vitamin D deficiency (<20 ng/dl) who met the inclusion criteria were sent to the Eye OPD from the Endocrinology OPD (case) were compared to 60 subjects with normal vitamin D levels (≥20 ng/dl) who attended the Eye OPD (controls). The examination of the tear film was done using Whatman filter paper in Schirmer test I and Schirmer test I (with anesthesia). The tear film break-up time (TFBUT) was determined by slit-lamp examination using the fluorescein stain, and scoring usingthe ocular surface disease index (OSDI) was done.
Results: A significant difference in the mean values of Schirmer I and Schirmer I test (with anesthesia) (P<0.001) was seen between the case and control groups. A significant difference in the mean values of TFBUT (P<0.001) and OSDI scores (P<0.01) was also seen between the two groups.
Conclusion: A positive association was found between vitamin D deficiency and dry eye on comparing the above parameters.
