Pathogen adaptation has contributed to the resurgence of pertussis. - GreenMedInfo Summary

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Abstract Title:

Complete Genome Sequences of 11 Bordetella pertussis Strains Representing the Pandemic ptxP3 Lineage.

Abstract Source:

Genome Announc. 2015;3(6). Epub 2015 Nov 25. PMID: 26607899

Abstract Author(s):

Marieke J Bart, Han G J van der Heide, Anne Zeddeman, Kees Heuvelman, Marjolein van Gent, Frits R Mooi

Article Affiliation:

Marieke J Bart

Abstract:

Pathogen adaptation has contributed to the resurgence of pertussis. To facilitate our understanding of this adaptation we report here 11 completely closed and annotated Bordetella pertussis genomes representing the pandemic ptxP3 lineage. Our analyses included six strains which do not produce the vaccine components pertactin and/or filamentous hemagglutinin.

Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Diseases : Pertussis : CK(146) : AC(25)
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus : CK(635) : AC(78), Vaccination: Pertussis : CK(246) : AC(43)

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Key Research Topics

Disease

Pertussis

Anti-Therapeutic Action

Vaccination: Diphtheria-Pertussis-Tetanus
Vaccination: Pertussis

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