Abstract Title:

Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men.

Abstract Source:

Obes Res. 2005 Aug;13(8):1335-43. PMID: 16129715

Abstract Author(s):

Michael P Godard, Brad A Johnson, Scott R Richmond

Article Affiliation:

University of Kansas, Department of Health, Sport and Exercise Sciences, Applied Physiology Laboratory, Lawrence, KS 66045, USA. [email protected]

Abstract:

OBJECTIVE: This study examined the effect of forskolin on body composition, testosterone, metabolic rate, and blood pressure in overweight and obese (BMI>or = 26 kg/m(2)) men.

RESEARCH METHODS AND PROCEDURE: Thirty subjects (forskolin, n = 15; placebo, n = 15) were studied in a randomized, double-blind, placebo-controlled study for 12 weeks.

RESULTS: Forskolin was shown to elicit favorable changes in body composition by significantly decreasing body fat percentage (BF%) and fat mass (FM) as determined by DXA compared with the placebo group (p

DISCUSSION: Oral ingestion of forskolin (250 mg of 10% forskolin extract twice a day) for a 12-week period was shown to favorably alter body composition while concurrently increasing bone mass and serum free testosterone levels in overweight and obese men. The results indicate that forskolin is a possible therapeutic agent for the management and treatment of obesity.

Study Type : Human Study

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