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Article Publish Status: FREE
Abstract Title:

The Role of Vitamin D in Brain Health: A Mini Literature Review.

Abstract Source:

Cureus. 2018 Jul 10 ;10(7):e2960. Epub 2018 Jul 10. PMID: 30214848

Abstract Author(s):

Ibrar Anjum, Syeda S Jaffery, Muniba Fayyaz, Zarak Samoo, Sheraz Anjum

Article Affiliation:

Ibrar Anjum

Abstract:

Vitamin D is vital for our body as it regulates calcium homeostasis and maintains bone integrity. In this article, we will discuss how vitamin D aids in the function of neuronal and glial tissue and the many health consequences in a person with vitamin D deficiency. Some of the effects of vitamin D deficiency that will be discussed include the development of dementia caused by the increase of cerebral soluble and insoluble amyloid-β (Aβ) peptides and a decrease of its anti-inflammatory/antioxidant properties, the link to depression by a reduction of the buffering of increased calcium in the brain, and vitamin D deficiency in expecting mothers linking to the development of autism and schizophrenic-like disorders, hypoxic brain injury, and other mental illnesses. Lastly, we will discuss how vitamin D deficiency is linked to the development of diabetes mellitus, its role in neuronal development and a decrease of microglial inflammatory function leading to increased brain infections.

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