n/a
Article Publish Status: FREE
Abstract Title:

Effect of Korean Red Ginseng intake on the survival duration of human immunodeficiency virus type 1 patients.

Abstract Source:

J Ginseng Res. 2017 Apr ;41(2):222-226. Epub 2017 Jan 6. PMID: 28413328

Abstract Author(s):

Young-Keol Cho, Jung-Eun Kim

Article Affiliation:

Young-Keol Cho

Abstract:

BACKGROUND: Long-term ginseng intake can increase longevity in healthy individuals. Here, we examined if long-term treatment with Panax ginseng Meyer (Korean Red Ginseng, KRG) can also enhance survival duration (SD) in patients with human immunodeficiency virus type 1 (HIV-1) infection.

METHODS: We retrospectively analyzed 252 HIV-1 patients diagnosed from 1986 to 2013 prior to the initiation of antiretroviral therapy. Overall, 162 patients were treated with KRG (3,947 ± 4,943 g) for 86 ± 63 mo. The effects of KRG on SD were analyzed according to the KRG intake level and the length of the follow-up period.

RESULTS: There were significant correlations between the total amount of KRG and SD in the KRG intake group (r = 0.64, p < 0.0001) as well as between total amount of KRG and mean annual decrease in CD4(+) T-cell count in all 252 patients (r = -0.17, p < 0.01). The annual decrease in CD4(+) T-cell count (change in cells/μL) was significantly slower in KRG-treated patients than in patients receiving no KRG (48 ± 40 vs. 106 ± 162; p < 0.001). The SD (in months) was also significantly longer in the KRG group than in the no-KRG group (101 ± 64 vs. 59 ± 40, p < 0.01).

CONCLUSION: KRG prolongs survival in HIV-1 patients, possibly by slowing the decrease in CD4(+) T-cell count.

Study Type : Human Study

Print Options


Key Research Topics

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2024 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.