Hydroxychavicol: a potent xanthine oxidase inhibitor obtained from the leaves of betel, Piper betle. - GreenMedInfo Summary
Hydroxychavicol: a potent xanthine oxidase inhibitor obtained from the leaves of betel, Piper betle.
J Nat Med. 2009 Jul ;63(3):355-9. Epub 2009 Apr 22. PMID: 19387769
Kazuya Murata
The screening of Piperaceous plants for xanthine oxidase inhibitory activity revealed that the extract of the leaves of Piper betle possesses potent activity. Activity-guided purification led us to obtain hydroxychavicol as an active principle. Hydroxychavicol is a more potent xanthine oxidase inhibitor than allopurinol, which is clinically used for the treatment of hyperuricemia.