Article Publish Status: FREE
Abstract Title:

Effect of Carrot Intake in the Prevention of Gastric Cancer: A Meta-Analysis.

Abstract Source:

J Gastric Cancer. 2015 Dec ;15(4):256-61. Epub 2015 Dec 31. PMID: 26819805

Abstract Author(s):

Hossein Fallahzadeh, Ali Jalali, Mahdieh Momayyezi, Soheila Bazm

Article Affiliation:

Hossein Fallahzadeh

Abstract:

PURPOSE: Gastric cancer is the third leading cause of cancer-related mortality, with the incidence and mortality being higher in men than in women. Various studies have shown that eating carrots may play a major role in the prevention of gastric cancer. We conducted a meta-analysis to determine the relationship between carrot consumption and gastric cancer.

MATERIALS AND METHODS: We searched multiple databases including PubMed, Cochrane Library, Scopus, ScienceDirect, and Persian databases like Scientific Information Database (SID) and IranMedx. The following search terms were used: stomach or gastric, neoplasm or cancer, carcinoma or tumor, and carrot. Statistical analyses were performed using Comprehensive Meta Analysis/2.0 software.

RESULTS: We retrieved 81 articles by searching the databases. After considering the inclusion and exclusion criteria, 5 articles were included in this study. The odds ratio (OR) obtained by fixed effects model showed that a 26% reduction in the risk of gastric cancer has been associated with the consumption of carrots) OR=0.74; 95% confidence interval=0.68~0.81; P<0.0001). According to funnel graph, the results showed that the possibility of a publication bias does not exist in this study.

CONCLUSIONS: The findings of this study showed an inverse relationship between the consumption of carrots and the risk of gastric cancer.

Study Type : Meta Analysis

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