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Article Publish Status: FREE
Abstract Title:

Effects of Lavender on Anxiety, Depression, and Physiological Parameters: Systematic Review and Meta-Analysis.

Abstract Source:

Asian Nurs Res (Korean Soc Nurs Sci). 2021 Dec ;15(5):279-290. Epub 2021 Nov 12. PMID: 34775136

Abstract Author(s):

Myoungsuk Kim, Eun Sook Nam, Yongmi Lee, Hyun-Ju Kang

Article Affiliation:

Myoungsuk Kim

Abstract:

PURPOSE: The recent evidence suggested substantial anxiolytic efficacy of lavender. The aim of this study was to examine the efficacy of lavender for anxiety, depression, and physiological parameters and to elucidate the differential effects of lavender on anxiety and depression by study characteristics.

METHODS: A systematic review and meta-analysis was performed following the PRISMA guidelines. We searched PubMed, Embase, Cochrane Library, Web of Science, and Cumulative Index of Nursing and Allied Health Literature databases for randomized controlled trials investigating the efficacy of lavender on anxiety, depression, or physiological parameters in humans. We assessed the risk of bias within studies with the revised Cochrane risk of bias tool for randomized trials. We used random effect model to estimate the average effect and computed bias-corrected standardized mean difference as effect size metric, Hedges'ĝ for all outcomes.

RESULTS: Lavender was superior to placebo or no treatment in reducing anxiety (Hedges'ĝ = -0.72, 95% confidence interval [CI] -0.90 to -0.55, p value<.001), depression (Hedges'ĝ = -0.43, 95% CI, -0.59 to -0.27, p value<.001), and systolic blood pressure (Hedges'ĝ = -0.23, 95% CI, -0.41to -0.05, p value = .01). The moderator analysis by meta-regression indicated that route of administration accounted 6.5% (p value = .187) for the heterogeneity in anxiolytic effects, sessions of treatment accounted 13.2% (p value = .055), and participants' healthstate accounted 8.9% (p value = .131) for the variance in anxiolytic effects.

CONCLUSION: Lavender aromatherapy showed substantial effect in reducing anxiety and depression, and sessions of administration increased the anxiolytic effects. The effects on physiological parameters showed small with inconsistent significances and randomized controlled trials on the effect of lavender on depression were scarce. Future trials on depression and physiological parameters are recommended, and increasing the sessions of administration is recommended.

Study Type : Meta Analysis, Review

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