n/a
Article Publish Status: FREE
Abstract Title:

Effects of artichoke leaf extract on hepatic ischemia-reperfusion injury.

Abstract Source:

Rev Assoc Med Bras (1992). 2022 Jan ;68(1):87-93. PMID: 34909970

Abstract Author(s):

Salih Celepli, Bayram Çolak, Pınar Celepli, İrem Bigat, Hatice Gül Batur, Furkan Soysal, Serdar Karakurt, Sema Hücümenoğlu, Kemal Kısmet, Mustafa Şahin

Article Affiliation:

Salih Celepli

Abstract:

OBJECTIVE: The aim of this study was to evaluate the hepatoprotective effect and mechanism of action of artichoke leaf extract in hepatic ischemia/reperfusion injury.

METHODS: Rats were divided into three groups such as sham, control, and artichoke leaf extract groups. Antioxidant enzyme activities and biochemical parameters were examined from the tissue and serum obtained from the subjects. Histopathological findings were scored semiquantitatively.

RESULTS: Statistically, the antioxidant activity was highest in the artichoke leaf extract group, the difference in biochemical parameters and C-reactive protein was significant compared with the control group, and the histopathological positive effects were found to be significantly higher.

CONCLUSIONS: As a result, artichoke leaf extract had a hepatoprotective effect and that this effect was related to the antioxidant and anti-inflammatory effects of artichoke.

Study Type : Animal Study

Print Options


Key Research Topics

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2024 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.