n/a
Article Publish Status: FREE
Abstract Title:

Echinacoside, an Inestimable Natural Product in Treatment of Neurological and other Disorders.

Abstract Source:

Molecules. 2018 May 18 ;23(5). Epub 2018 May 18. PMID: 29783690

Abstract Author(s):

Jingjing Liu, Lingling Yang, Yanhong Dong, Bo Zhang, Xueqin Ma

Article Affiliation:

Jingjing Liu

Abstract:

Echinacoside (ECH), a natural phenylethanoid glycoside, was first isolated fromDC. (Compositae) sixty years ago. It was found to possess numerous pharmacologically beneficial activities for human health, especially the neuroprotective and cardiovascular effects. Although ECH showed promising potential for treatment of Parkinson's and Alzheimer's diseases, some important issues arose. These included the identification of active metabolites as having poor bioavailability in prototype form, the definite molecular signal pathways or targets of ECH with the above effects, and limited reliable clinical trials. Thus, it remains unresolved as to whether scientific research can reasonably make use of this natural compound. A systematic summary and knowledge of future prospects are necessary to facilitate further studies for this natural product. The present review generalizes and analyzes the current knowledge on ECH, including its broad distribution, different preparation technologies, poor pharmacokinetics and kinds of therapeutic uses, and the future perspectives of its potential application.

Study Type : Review

Print Options


Key Research Topics

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2024 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.