Abstract Title:

Anti-hepatitis C virus effect of citrus unshiu peel and its active ingredient nobiletin.

Abstract Source:

Am J Chin Med. 2005;33(1):87-94. PMID: 15844836

Abstract Author(s):

Megumi Suzuki, Kenroh Sasaki, Fumihiko Yoshizaki, Katsuji Oguchi, Min Fujisawa, Jong-Chol Cyong

Abstract:

hepatitis C virus (HCV) absorption in MOLT-4 cells (a human lymphoblastoid leukemia cell line). By reverse transcription polymerase chain reaction (RT-PCR), we showed that both the ethyl acetate layer of Citrus unshiu peel extract and fraction 7 decreased HCV absorption in MOLT-4 cells. Furthermore, we demonstrated that 3',4',5,6,7,8-hexamethoxyflavone (nobiletin) is the active ingredient that markedly inhibited HCV infection in MOLT-4 cells.

Study Type : In Vitro Study

Print Options


Key Research Topics

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2024 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.