Antiproliferative and antiviral activity of methanolic extracts from Sardinian Maltese Mushroom (Cynomorium coccineum L.). - GreenMedInfo Summary
Antiproliferative and antiviral activity of methanolic extracts from Sardinian Maltese Mushroom (L.).
Nat Prod Res. 2019 Oct 17:1-5. Epub 2019 Oct 17. PMID: 31621410
Sarah Vascellari
is a non-photosynthetic plant that grows in Mediterranean countries and that is amply used in the traditional medicine. The aim of this study was to extend previous studies on the chemical and biological properties ofevaluating the potential antiviral and antiproliferative activity of the methanolic extract. The MTT assay was used for thecytotoxic studies against human cancer-derived cell lines, while both MTT and plaque reduction (PRT) methods were used to evaluate the potential inhibitory effect of the extract against a panel of mammal viruses. The results obtained showed no selective activity against any DNA and RNA virus but revealed an interesting antiproliferative activity against human leukaemia-derived cell lines.