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Article Publish Status: FREE
Abstract Title:

Andrographolide, a natural anti-inflammatory agent: An Update.

Abstract Source:

Front Pharmacol. 2022 ;13:920435. Epub 2022 Sep 27. PMID: 36238575

Abstract Author(s):

Xiaohong Li, Weichen Yuan, Jibiao Wu, Jianhua Zhen, Qihui Sun, Minmin Yu

Article Affiliation:

Xiaohong Li

Abstract:

Botanicals have attracted much attention in the field of anti-inflammatory due to their good pharmacological activity and efficacy.is a natural plant ingredient that is widely used around the world. Andrographolide is the main active ingredient derived from, which has a good effect on the treatment of inflammatory diseases. This article reviews the application, anti-inflammatory mechanism and molecular targets of andrographolide in different inflammatory diseases, including respiratory, digestive, immune, nervous, cardiovascular, skeletal, and tumor system diseases. And describe its toxicity and explain its safety. Studies have shown that andrographolide can be used to treat inflammatory lesions of various systemic diseases. In particular, it acts on many inflammation-related signalling pathways. The future direction of andrographolide research is also introduced, as is the recent research that indicates its potential clinical application as an anti-inflammatory agent.

Study Type : Review

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