Immunomodulatory: Th17 downregulation

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60 Substances Researched for Immunomodulatory: Th17 downregulation
NameACCKFocus
Zataria multiflora313Locked
Curcumin211Locked
Lactobacillus plantarum110Locked
Omega-3 Fatty Acids110Locked
Resveratrol47Locked
Berberine36Locked
EGCG (Epigallocatechin gallate)36Locked
Apigenin15Locked
Arctigenin35Locked
Fisetin15Locked
Vitamin D35Locked
Burdock24Locked
Ginseng (Korean)24Locked
Mangosteen24Locked
Paeoniflorin24Locked
Sulforaphane24Locked
Cannabidiol23Locked
Ginsenosides23Locked
Honeysuckle23Locked
Peony23Locked
Acetic Acid12Locked
Agaricus Blazei12Locked
Astragalus12Locked
Beta-Elemene12Locked
Black Pepper12Locked
Butyrate12Locked
Cannabis12Locked
Cinnamon12Locked
Coenzyme Q1012Locked
Cucurbitacin E 12Locked
DHA (Docosahexaenoic Acid)12Locked
Delta-tetrahydrocannabinol (THC)12Locked
Dong Quai12Locked
Evening Primrose Oil12Locked
Flavonoids12Locked
Flaxseed12Locked
Gallic Acid12Locked
Hemp Seed12Locked
Hydrogen Water12Locked
Indole-3-Carbinol12Locked
Lactobacillus reuteri12Locked
Lactobacillus rhamnosus GG12Locked
Licorice12Locked
Mangiferin12Locked
Okra12Locked
Probiotics22Locked
Tanshinone IIA12Locked
Vinegar12Locked
Astragaloside11Locked
Betulinic acid11Locked
Carnosol11Locked
Eriodictyol11Locked
Melatonin11Locked
Panax Notoginseng11Locked
Parthenolide11Locked
Piperlongumine 11Locked
Punicalagin11Locked
Red Wine Extract11Locked
Tangeretin 11Locked
Thymol11Locked

View the Evidence:
91 Abstracts with Immunomodulatory: Th17 downregulation Research

[+]

Immunomodulatory effects of nanocurcumin on Th17 cell responses in mild and severe COVID-19 patients.Dec 27, 2020

Pubmed Data : J Cell Physiol. 2020 Dec 28. Epub 2020 Dec 28. PMID: 33372280
Article Published Date : Dec 27, 2020
Study Type : Human Study
Additional Links
Substances : Curcumin
Diseases : Coronavirus Infection
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Lactobacillus plantarum IS-10506 supplementation reduced SCORAD in children with atopic dermatitis.Oct 12, 2017

Pubmed Data : Benef Microbes. 2017 Oct 13 ;8(5):833-840. Epub 2017 Oct 12. PMID: 29022387
Article Published Date : Oct 12, 2017
Study Type : Human Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Atopic Dermatitis
Pharmacological Actions : Immunomodulatory: Th17 downregulation, Interferon Gamma Reducer, Interleukin-4 downregulation
[+]

Omega 3 supplementation can regulate inflammatory states in gas station workers.Mar 12, 2020

Pubmed Data : J Interferon Cytokine Res. 2020 Mar 13. Epub 2020 Mar 13. PMID: 32176565
Article Published Date : Mar 12, 2020
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation, Interferon Gamma Reducer, Interleukin-10 upregulation, Transforming growth factor beta (TGF-β) upregulation
[+]

Oral administration of Zataria multiflora extract decreases IL-17 expression in perennial allergic rhinitis.Mar 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Rep Biochem Mol Biol. 2018 Apr ;6(2):203-207. PMID: 29766004
Article Published Date : Mar 31, 2018
Study Type : Human Study
Additional Links
Substances : Zataria multiflora
Diseases : Allergic Rhinitis
Pharmacological Actions : Immunomodulatory: Th17 downregulation
[+]

Significant immunomodulatory and hepatoprotective impacts of Silymarin in MS patients.Apr 28, 2021

Pubmed Data : Int Immunopharmacol. 2021 Apr 29 ;97:107715. Epub 2021 Apr 29. PMID: 33933848
Article Published Date : Apr 28, 2021
Study Type : Human Study
Additional Links
Substances : Silibinin
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-10 upregulation
[+]

Modulation of Th17 proliferation and IL-17A gene expression by acetylated form of apigenin in patients with multiple sclerosis.Feb 25, 2020

Pubmed Data : Immunol Invest. 2020 Feb 26:1-14. Epub 2020 Feb 26. PMID: 32100582
Article Published Date : Feb 25, 2020
Study Type : Human In Vitro
Additional Links
Substances : Apigenin
Diseases : Multiple Sclerosis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

These results suggest that fisetin has a great potential to be developed as an effective and inexpensive agent for the treatment of psoriasis.Sep 14, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cells. 2019 Sep 15 ;8(9). Epub 2019 Sep 15. PMID: 31540162
Article Published Date : Sep 14, 2019
Study Type : Human In Vitro
Additional Links
Substances : Fisetin
Diseases : Psoriasis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory: Th17 downregulation, Interferon Gamma Reducer
[+]

1,25(OH)2 D3 inhibited Th17 cells differentiation via regulating the NF-κB activity and expression of IL-17.Sep 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Prolif. 2018 Oct ;51(5):e12461. Epub 2018 Apr 24. PMID: 29687949
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Vitamin D
Diseases : Tuberculosis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, NF-kappaB Inhibitor
[+]

Amelioration of experimental autoimmune encephalomyelitis by β-elemene treatment is associated with Th17 and Treg cell balance.Apr 30, 2011

Pubmed Data : J Mol Neurosci. 2011 May ;44(1):31-40. Epub 2011 Jan 19. PMID: 21246417
Article Published Date : Apr 30, 2011
Study Type : Animal Study
Additional Links
Substances : Beta-Elemene
Diseases : Multiple Sclerosis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-23 Downregulation, Interleukin-6 Downregulation
[+]

Angelica sinensis polysaccharide prevents mitochondrial apoptosis by regulating the Treg/Th17 ratio in aplastic anemia.Jun 21, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Med Ther. 2020 Jun 22 ;20(1):192. Epub 2020 Jun 22. PMID: 32571324
Article Published Date : Jun 21, 2020
Study Type : Animal Study
Additional Links
Substances : Dong Quai
Diseases : Anemia: Aplastic
Pharmacological Actions : Immunomodulatory: Th17 downregulation
Additional Keywords : Polysaccharides
[+]

Anti-allergic rhinitis activity of α-lipoic acid via balancing Th17/Treg expression and enhancing Nrf2/HO-1 pathway signaling.Jul 26, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2020 Jul 27 ;10(1):12528. Epub 2020 Jul 27. PMID: 32719431
Article Published Date : Jul 26, 2020
Study Type : Animal Study
Additional Links
Diseases : Allergic Rhinitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Immunomodulatory: Th17 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Arctigenin ameliorates colitis through down-regulating the differentiation of Th1 and Th17 cells via mTORC1 pathway. Aug 14, 2015

Pubmed Data : Biochem Pharmacol. 2015 Aug 15 ;96(4):323-36. Epub 2015 Jun 11. PMID: 26074264
Article Published Date : Aug 14, 2015
Study Type : Animal Study
Additional Links
Substances : Arctigenin, Burdock
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Arctigenin may have anti-inflammatory and immunosuppressive properties via inhibiting Th17 cells.Oct 05, 2015

Pubmed Data : Mol Neurobiol. 2015 Oct 6. Epub 2015 Oct 6. PMID: 26440666
Article Published Date : Oct 05, 2015
Study Type : Animal Study
Additional Links
Substances : Arctigenin, Burdock
Diseases : Autoimmune Diseases, Brain Inflammation , Multiple Sclerosis
Pharmacological Actions : Immunomodulatory: Th17 downregulation, Immunosuppressive Agents
[+]

Astilbin ameliorates experimental autoimmune myasthenia gravis.Jan 14, 2016

Pubmed Data : J Neuroimmunol. 2016 09 15 ;298:138-45. Epub 2016 Jul 20. PMID: 27609287
Article Published Date : Jan 14, 2016
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Myasthenia Gravis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Astragalus polysaccharide exerts an effective therapeutic effect against experimental colitis by recovering the functional status of Treg cells.Mar 20, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2016 Mar 21 ;22(11):3175-85. PMID: 27003994
Article Published Date : Mar 20, 2016
Study Type : Animal Study
Additional Links
Substances : Astragalus
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Astragalus polysaccharide relieves inflammatory responses in guinea pigs with allergic rhinitis.May 17, 2022

Pubmed Data : Am J Rhinol Allergy. 2022 May 18:19458924221098847. Epub 2022 May 18. PMID: 35585694
Article Published Date : May 17, 2022
Study Type : Animal Study
Additional Links
Substances : Astragalus
Diseases : Allergic Rhinitis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory: Th17 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Autism is associated with dysregulation of transcription factor signalling that can be corrected by resveratrol treatment in mice. Aug 29, 2016

Pubmed Data : Mol Neurobiol. 2016 Aug 30. Epub 2016 Aug 30. PMID: 27578011
Article Published Date : Aug 29, 2016
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Autism, Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory: Th17 downregulation, MicroRNA modulator
[+]

Berberine has anti-inflammatory effects on H. pylori-induced chronic gastritis.Jan 17, 2018

Pubmed Data : J Cell Biochem. 2018 Jan 18. Epub 2018 Jan 18. PMID: 29345340
Article Published Date : Jan 17, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Helicobacter Pylori Infection
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory: Th17 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Berberine prevents ulcerative colitis by modifying gut microbiota and regulating the balance of Treg/Th17.Dec 31, 2017

Pubmed Data : Front Pharmacol. 2018 ;9:571. Epub 2018 May 31. PMID: 29904348
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Ulcerative Colitis
Pharmacological Actions : Immunomodulatory: Th17 downregulation
Additional Keywords : Microbiota
[+]

Cucurbitacin E ameliorates acute graft-versus-host disease.Sep 17, 2018

Pubmed Data : Immunol Lett. 2018 Sep 18 ;203:62-69. Epub 2018 Sep 18. PMID: 30240636
Article Published Date : Sep 17, 2018
Study Type : Animal Study
Additional Links
Substances : Cucurbitacin E
Diseases : Graft vs Host Disease
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, STAT3 Inhibitor
[+]

Delphinidin diminishes in vitro interferon-γ and interleukin-17 producing cells in patients with psoriatic disease.Nov 24, 2021

Pubmed Data : Immunol Res. 2021 Nov 25. Epub 2021 Nov 25. PMID: 34825313
Article Published Date : Nov 24, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Delphinidin
Diseases : Psoriatic Arthritis
Pharmacological Actions : Immunomodulatory: Th17 downregulation
[+]

Dietary indole-3-carbinol alleviated spleen enlargement, enhanced IgG response in C3H/HeN mice infected with Citrobacter rodentium.Oct 14, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 Oct 15 ;12(10). Epub 2020 Oct 15. PMID: 33076301
Article Published Date : Oct 14, 2020
Study Type : Animal Study
Additional Links
Substances : Indole-3-Carbinol
Diseases : Citrobacter Infection
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Docosahexaenoic acid Docosahexaenoic acid prevents dendritic cell maturation, inhibits antigen-specific Th1/Th17 differentiation and suppresses experimental autoimmune encephalomyelitis suppresses experimental autoimmune encephalomyelitis.Sep 18, 2010

Pubmed Data : Brain Behav Immun. 2010 Sep 18. Epub 2010 Sep 18. PMID: 20854895
Article Published Date : Sep 18, 2010
Study Type : Animal Study
Additional Links
Substances : DHA (Docosahexaenoic Acid)
Diseases : Multiple Sclerosis
Pharmacological Actions : Immunomodulatory: Th17 downregulation
[+]

EGCG decreased the arthritis index and showed protective effects against joint destruction in collagen-induced arthritis mice.Mar 07, 2016

Pubmed Data : J Leukoc Biol. 2016 Mar 8. Epub 2016 Mar 8. PMID: 26957211
Article Published Date : Mar 07, 2016
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Heme oxygenase-1 up-regulation, Immunomodulatory: Th17 downregulation, NF-E2-Related Factor-2 (Nrf2) Modulator, STAT3 Inhibitor
[+]

EGCG has an antiarthritic effect by regulating the oxidative-antioxidant balance and cytokine levels.Nov 18, 2019

Pubmed Data : Biotechnol Appl Biochem. 2019 Nov 19. Epub 2019 Nov 19. PMID: 31746064
Article Published Date : Nov 18, 2019
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Immunomodulatory: Th17 downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Evening primrose/hemp seed oil was able to reduce the severity of autoimmune encephalomyelitis and inhibited the development of the disease.Apr 15, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Allergy Asthma Immunol. 2020 Apr 16 ;19(2):183-192. Epub 2020 Apr 16. PMID: 32372631
Article Published Date : Apr 15, 2020
Study Type : Animal Study
Additional Links
Substances : Evening Primrose Oil, Hemp Seed
Diseases : Multiple Sclerosis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, Interferon Gamma Reducer, Interleukin-10 upregulation
[+]

Flos Abelmoschus manihot extract attenuates DSS-induced colitis by regulating gut microbiota and Th17/Treg balance.Aug 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Sep ;117:109162. Epub 2019 Jun 26. PMID: 31254739
Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Okra
Diseases : Colitis
Pharmacological Actions : Gastrointestinal Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Gallic acid may be used as a therapeutic agent for allergic rhinitis.Mar 14, 2019

Pubmed Data : Int Immunopharmacol. 2019 Mar 15 ;70:512-519. Epub 2019 Mar 15. PMID: 30884431
Article Published Date : Mar 14, 2019
Study Type : Animal Study
Additional Links
Substances : Gallic Acid
Diseases : Allergic Rhinitis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, interleukin-13 down-regulation, Interleukin-4 downregulation, Interleukin-5 downregulation
[+]

Green tea catechins alleviate autoimmune symptoms and visual impairment in a murine model for human chronic intraocular inflammation.Jan 18, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2019 02 19 ;9(1):2301. Epub 2019 Feb 19. PMID: 30783194
Article Published Date : Jan 18, 2019
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Autoimmune Diseases, Uveitis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Hydrogen rich water may have great potential in the treatment of Multiple sclerosis.May 14, 2016

Pubmed Data : J Neuroimmunol. 2016 May 15 ;294:6-13. Epub 2016 Mar 14. PMID: 27138092
Article Published Date : May 14, 2016
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Multiple Sclerosis
Pharmacological Actions : Immunomodulatory: Th17 downregulation, Neuroprotective Agents
[+]

Immunomodulatory effects of licochalcone A on experimental autoimmune encephalomyelitis.May 31, 2014

Pubmed Data : J Pharm Pharmacol. 2014 Jun ;66(6):886-94. Epub 2014 Jan 22. PMID: 24447171
Article Published Date : May 31, 2014
Study Type : Animal Study
Additional Links
Substances : Licorice
Diseases : Multiple Sclerosis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, Interferon Gamma Reducer, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Isogarcinol has the potential to be an effective therapeutic agent of low toxicity for treating MS and other autoimmune diseases.Nov 29, 2016

Pubmed Data : J Agric Food Chem. 2016 Nov 30 ;64(47):9012-9021. Epub 2016 Nov 16. PMID: 27933873
Article Published Date : Nov 29, 2016
Study Type : Animal Study
Additional Links
Substances : Mangosteen
Diseases : Autoimmune Diseases, Multiple Sclerosis
Pharmacological Actions : Immunomodulatory: Th17 downregulation
[+]

Isogarcinol is a promising immunosuppressive agent for treating psoriasis.Jan 31, 2017

Pubmed Data : J Agric Food Chem. 2017 Feb 1 ;65(4):846-857. Epub 2017 Jan 24. PMID: 28081600
Article Published Date : Jan 31, 2017
Study Type : Animal Study
Additional Links
Substances : Mangosteen
Diseases : Lipopolysaccharide-Induced Toxicity, Psoriasis
Pharmacological Actions : Immunomodulatory: Th17 downregulation, Immunosuppressive Agents, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-23 Downregulation, Interleukin-2 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ketogenic diets alter the gut microbiome resulting in decreased intestinal Th17 cells. May 13, 2020

Pubmed Data : Cell. 2020 May 14. Epub 2020 May 14. PMID: 32437658
Article Published Date : May 13, 2020
Study Type : Animal Study
Additional Links
Diseases : High Fat Diet
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Immunomodulatory: Th17 downregulation
[+]

Korean red ginseng extract alleviated neurological impairment of myelin oligodendrocyte glycoprotein induced mouse model of chronic experimental autoimmune encephalomyelitis.Apr 06, 2015

Pubmed Data : Mol Neurobiol. 2015 Apr 7. Epub 2015 Apr 7. PMID: 25846819
Article Published Date : Apr 06, 2015
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean), Ginsenosides
Diseases : Autoimmune Diseases, Encephalomyelitis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-1 beta downregulation, MicroRNA modulator, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Lactobacillus casei HY2782 and Pueraria lobata root extract complex ameliorates particulate matter-induced airway inflammation.Jun 29, 2022

Pubmed Data : Prev Nutr Food Sci. 2022 Jun 30 ;27(2):188-197. PMID: 35919572
Article Published Date : Jun 29, 2022
Study Type : Animal Study
Additional Links
Substances : Kudzu, Lactobacillus casei
Diseases : Air Pollution Linked Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory: Th17 downregulation, interleukin-13 down-regulation, Interleukin-4 downregulation, Interleukin-5 downregulation
[+]

Lactobacillus plantarum strains attenuated DSS-induced colitis.Apr 11, 2022

Pubmed Data : Int Microbiol. 2022 Apr 12. Epub 2022 Apr 12. PMID: 35414032
Article Published Date : Apr 11, 2022
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Immunomodulatory: Th17 downregulation, Interleukin-22 Downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Lactobacillus reuteri reduces the severity of experimental autoimmune encephalomyelitis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2019 ;10:385. Epub 2019 Mar 7. PMID: 30899262
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Lactobacillus reuteri
Diseases : Multiple Sclerosis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, Interferon Gamma Reducer
[+]

Lactobacillus rhammosus GG might be an additional or supplementary therapy for allergic airway diseases.Mar 22, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Microbiol Immunol Infect. 2019 Mar 23. Epub 2019 Mar 23. PMID: 30952512
Article Published Date : Mar 22, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus GG
Diseases : Asthma
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory: Th17 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Mangiferin may ameliorate colitis by the restoration of disturbed Th17/Treg cells and inhibition of macrophage activation.Apr 30, 2016

Pubmed Data : Int Immunopharmacol. 2016 May ;34:220-8. Epub 2016 Mar 9. PMID: 26971225
Article Published Date : Apr 30, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Mangiferin
Diseases : Colitis
Pharmacological Actions : Immunomodulatory: Th17 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Oral administration of cinnamon powder may be beneficial in MS patients and that no other existing anti-MS therapies could be so economical and trouble free as this approach.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(1):e0116566. Epub 2015 Jan 8. PMID: 25569428
Article Published Date : Dec 31, 2014
Study Type : Transgenic Animal Study
Additional Links
Substances : Cinnamon
Diseases : Encephalomyelitis, Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation
Additional Keywords : Dose Response, Gene Expression Regulation
[+]

Oral berberine exerted anti-arthritic effect through inhibiting Th17 cell response.Jun 20, 2017

Pubmed Data : FEBS J. 2017 Jun 21. Epub 2017 Jun 21. PMID: 28636167
Article Published Date : Jun 20, 2017
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Arthritis
Pharmacological Actions : Immunomodulatory: Th17 downregulation
[+]

Paeoniflorin ameliorates ulcerative colitis by modulating the dendritic cell-mediated TH17/Treg balanceMay 28, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Inflammopharmacology. 2020 May 29. Epub 2020 May 29. PMID: 32472435
Article Published Date : May 28, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Paeoniflorin
Diseases : Ulcerative Colitis
Pharmacological Actions : Gastrointestinal Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Paeoniflorin inhibits Th1 and Th17 cells in gut-associated lymphoid tissues to produce anti-arthritis activities.Jul 14, 2019

Pubmed Data : Inflammopharmacology. 2019 Jul 15. Epub 2019 Jul 15. PMID: 31309485
Article Published Date : Jul 14, 2019
Study Type : Insect Study
Additional Links
Substances : Paeoniflorin
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Parthenolide suppresses T helper 17 and alleviates experimental autoimmune encephalomyelitis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2022 ;13:856694. Epub 2022 Apr 20. PMID: 35514960
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Parthenolide
Diseases : Inflammation, Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory: Th17 downregulation, NF-kappaB Inhibitor
[+]

Physical exercise attenuates experimental autoimmune encephalomyelitis.Dec 31, 2016

Pubmed Data : Mol Neurobiol. 2017 08 ;54(6):4723-4737. Epub 2016 Jul 22. PMID: 27447807
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Encephalomyelitis, Multiple Sclerosis
Therapeutic Actions : Exercise
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Prophylactic effects of Lonicera japonica extract on dextran sulphate sodium-induced colitis.Jan 27, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Nutr. 2013 Jan 28 ;109(2):283-92. Epub 2012 May 9. PMID: 22569277
Article Published Date : Jan 27, 2013
Study Type : Animal Study
Additional Links
Substances : Honeysuckle
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory: Th17 downregulation, Interferon Gamma Reducer, Interleukin-12 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Prunella vulgaris can improve the pregnancy outcomes of experimental autoimmune thyroiditis.Dec 23, 2021

Pubmed Data : J Reprod Immunol. 2021 Dec 24 ;149:103469. Epub 2021 Dec 24. PMID: 34979369
Article Published Date : Dec 23, 2021
Study Type : Animal Study
Additional Links
Substances : Prunella vulgaris
Diseases : Thyroiditis: Autoimmune
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Red ginseng extracts can ameliorate arthritis in mice with CIA by targeting pathogenic Th17 and osteoclast differentiation, suggesting a novel therapy for treatment of RA.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mediators Inflamm. 2014 ;2014:351856. Epub 2014 Jul 23. PMID: 25147435
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Arthritis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory: Th17 downregulation
Additional Keywords : Plant Extracts
[+]

Resveratrol modulates the gut microbiota to prevent murine colitis development.Mar 20, 2019

Pubmed Data : J Leukoc Biol. 2019 Mar 21. Epub 2019 Mar 21. PMID: 30897248
Article Published Date : Mar 20, 2019
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Colitis
Pharmacological Actions : Gastrointestinal Agents, Immunomodulatory: Th17 downregulation
[+]

Resveratrol-mediated attenuation of colitis may be regulated by miR-31 through induction of Tregs and miR-31 may serve as a therapeutic target for human colitis.Dec 31, 2019

Pubmed Data : Mol Nutr Food Res. 2020 01 ;64(1):e1900633. Epub 2019 Dec 11. PMID: 31730734
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Colitis
Pharmacological Actions : Immunomodulatory: Th17 downregulation, MicroRNA modulator
[+]

Sulforaphane ameliorates autism-like symptoms through suppression of Th17 related signalling and rectification of oxidant-antioxidant imbalance.Feb 18, 2019

Pubmed Data : Behav Brain Res. 2019 Feb 19 ;364:213-224. Epub 2019 Feb 19. PMID: 30790585
Article Published Date : Feb 18, 2019
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Autism
Pharmacological Actions : Antioxidants, Immunomodulatory: Th17 downregulation, Nrf2 activation
[+]

Sulforaphane treatment reverses corticosteroid resistance in a mixed granulocytic mouse model of asthma.Jul 14, 2019

Pubmed Data : Eur J Pharmacol. 2019 Jul 15 ;855:276-284. Epub 2019 May 14. PMID: 31100413
Article Published Date : Jul 14, 2019
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Asthma
Pharmacological Actions : Antioxidants, Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-23 Downregulation, Interleukin-6 Downregulation
[+]

Tanshinone IIA attenuates experimental autoimmune encephalomyelitis in rats.Jul 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2016 Aug ;14(2):1601-9. Epub 2016 Jun 23. PMID: 27357729
Article Published Date : Jul 31, 2016
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Multiple Sclerosis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-23 Downregulation
[+]

THC treatment during Delayed-type hypersensitivity response can simultaneously inhibit Th1/Th17 activation via regulation of microRNA expression.Mar 31, 2016

Pubmed Data : J Mol Med (Berl). 2016 Apr 1. Epub 2016 Apr 1. PMID: 27038180
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Cannabis, Delta-tetrahydrocannabinol (THC)
Diseases : Hypersensitivity
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation, MicroRNA modulator
[+]

The consumption of phenolic and protein compounds extracted from flaxseeds has a protective effect on TNBS-induced colitis.Jun 21, 2018

Pubmed Data : Mol Nutr Food Res. 2018 Jun 22:e1800088. Epub 2018 Jun 22. PMID: 29932491
Article Published Date : Jun 21, 2018
Study Type : Animal Study
Additional Links
Substances : Flaxseed
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory: Th17 downregulation
[+]

The effect of Zataria multiflora on Th1/Th2 and Th17/T regulatory in a mouse model of allergic asthma.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2017 ;8:458. Epub 2017 Aug 7. PMID: 28824424
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Zataria multiflora
Diseases : Asthma
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-4 downregulation
[+]

The significance of Agaricus blazei as an immunomodulator of the level of IL-17 in Balb/C mice with atherosclerosis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cent Eur J Immunol. 2020 ;45(1):1-8. PMID: 32425674
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Agaricus Blazei
Diseases : Atherosclerosis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

These obtained results suggest that P. nigrum fruit extract has the promising strategy for immunotherapy in allergic rhinitis disease.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Jan ;109:1915-1923. Epub 2018 Nov 26. PMID: 30551446
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Black Pepper
Diseases : Allergic Rhinitis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation, STAT3 Inhibitor
[+]

These results provide insights into butyrate as a potential therapeutic for the treatment of inflammatory bowel disease.Mar 26, 2019

Pubmed Data : Inflamm Bowel Dis. 2019 Mar 27. Epub 2019 Mar 27. PMID: 30918945
Article Published Date : Mar 26, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Butyrate
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-10 upregulation
[+]

These results suggest that vinegar supplementation might provide a new dietary strategy for the prevention of ulcerative colitis.Feb 09, 2016

Pubmed Data : J Agric Food Chem. 2016 Feb 10 ;64(5):1111-21. Epub 2016 Feb 1. PMID: 26795553
Article Published Date : Feb 09, 2016
Study Type : Animal Study
Additional Links
Substances : Acetic Acid, Vinegar
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

These results support the use of CoQ10 as a potential targeted therapy for the treatment of colitis.Aug 31, 2017

Pubmed Data : J Med Food. 2017 Sep ;20(9):821-829. Epub 2017 Aug 17. PMID: 28816577
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory: Th17 downregulation, STAT3 Inhibitor
[+]

This data suggests that CBD exerts its immunoregulatory effects via induction of CD4(+)CD25(-)CD69(+)LAG3(+) cells.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2015 ;12:52. Epub 2015 Mar 15. PMID: 25880134
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Total glucosides of peony could be a potential therapeutic agent for multiple sclerosis.Jul 14, 2015

Pubmed Data : J Neuroimmunol. 2015 Jul 15 ;284:67-73. Epub 2015 May 12. PMID: 26025060
Article Published Date : Jul 14, 2015
Study Type : Animal Study
Additional Links
Substances : Peony
Diseases : Multiple Sclerosis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
Additional Keywords : Phytotherapy
[+]

Vitamin D down-regulates the expression of inflammatory cytokines, chemokines and chemokine receptors in experimental autoimmune encephalomyelitis.Feb 14, 2018

Pubmed Data : Nutr Neurosci. 2018 Feb 15:1-13. Epub 2018 Feb 15. PMID: 29447086
Article Published Date : Feb 14, 2018
Study Type : Animal Study
Additional Links
Substances : Vitamin D
Diseases : Encephalomyelitis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-23 Downregulation
[+]

Vitamin D has an effect on airway inflammation and Th17/Treg balance in asthmatic mice.Aug 29, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Kaohsiung J Med Sci. 2021 Aug 30. Epub 2021 Aug 30. PMID: 34460994
Article Published Date : Aug 29, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Vitamin D
Diseases : Asthma
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory: Th17 downregulation, Interleukin-10 upregulation, Transforming growth factor beta (TGF-β) upregulation
[+]

A critical regulation of Th17 cell responses and autoimmune neuro-inflammation by ginsenoside Rg3.Jan 09, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomolecules. 2020 Jan 10 ;10(1). Epub 2020 Jan 10. PMID: 31936879
Article Published Date : Jan 09, 2020
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Autoimmune Diseases, Brain Inflammation
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

A novel probiotic mixture, slows down the tumor growth significantly and reduces the tumor size and weight by 40% compared with the control.Feb 15, 2016

Pubmed Data : Proc Natl Acad Sci U S A. 2016 Feb 16. Epub 2016 Feb 16. PMID: 26884164
Article Published Date : Feb 15, 2016
Study Type : In Vitro Study
Additional Links
Substances : Probiotics
Diseases : Gastrointestinal Inflammation, Liver Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Chemopreventive, Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-17 downregulation
Additional Keywords : Microbiota
[+]

A review of the immunomodulatory role of vitamin D.Aug 25, 2018

Pubmed Data : Adv Exp Med Biol. 2018 Aug 26. Epub 2018 Aug 26. PMID: 30143987
Article Published Date : Aug 25, 2018
Study Type : Review
Additional Links
Substances : Vitamin D
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Astragaloside could be used for the treatment of multiple sclerosis and other similar autoimmune diseases.Oct 28, 2018

Pubmed Data : Toxicol Appl Pharmacol. 2018 Oct 29 ;362:105-115. Epub 2018 Oct 29. PMID: 30385269
Article Published Date : Oct 28, 2018
Study Type : In Vitro Study
Additional Links
Substances : Astragaloside
Diseases : Autoimmune Diseases, Multiple Sclerosis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Astragaloside Ⅳ alleviates ulcerative colitis by regulating the balance of Th17/Treg cells.Jun 18, 2022

Pubmed Data : Phytomedicine. 2022 Jun 19 ;104:154287. Epub 2022 Jun 19. PMID: 35752072
Article Published Date : Jun 18, 2022
Study Type : In Vitro Study
Additional Links
Substances : Astragaloside
Diseases : Ulcerative Colitis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Betulinic acid suppresses Th17 response and ameliorates psoriasis-like murine skin inflammation.Jul 31, 2019

Pubmed Data : Int Immunopharmacol. 2019 Aug ;73:343-352. Epub 2019 May 23. PMID: 31129421
Article Published Date : Jul 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Betulinic acid
Diseases : Psoriasis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory: Th17 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Carnosol has enormous potential for development as a therapeutic agent for autoimmune diseases such as multiple sclerosis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2018 ;9:1807. Epub 2018 Aug 13. PMID: 30150982
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carnosol
Diseases : Autoimmune Diseases, Encephalomyelitis, Multiple Sclerosis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Curcumin can modulate Th17/Treg balance specifically on CD4+ T cells of SLE patients without affecting healthy subjects.Dec 31, 2015

Pubmed Data : Cent Eur J Immunol. 2016 ;40(4):461-9. Epub 2016 Jan 15. PMID: 26862311
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Systemic Lupus Erythematosus
Pharmacological Actions : Immunomodulatory: Th17 downregulation
[+]

Eriodictyol suppresses Th17 differentiation and the pathogenesis of experimental autoimmune encephalomyelitis.Jul 31, 2020

Pubmed Data : Food Funct. 2020 Aug 1 ;11(8):6875-6888. Epub 2020 Jul 20. PMID: 32686813
Article Published Date : Jul 31, 2020
Study Type : In Vitro Study
Additional Links
Substances : Eriodictyol
Diseases : Multiple Sclerosis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

HS-23, a Lonicera japonica extract, reverses sepsis-induced immunosuppression by inhibiting lymphocyte apoptosis.Aug 01, 2015

Pubmed Data : J Ethnopharmacol. 2015 Aug 2 ;171:231-9. Epub 2015 Jun 9. PMID: 26068428
Article Published Date : Aug 01, 2015
Study Type : In Vitro Study
Additional Links
Substances : Honeysuckle
Diseases : Sepsis
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Immunomodulatory, Immunomodulatory: Th17 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Melatonin exerts immunoregulatory effects by balancing peripheral effector and regulatory T helper cells in myasthenia gravis.Jan 01, 2020

Pubmed Data : Aging (Albany NY). 2020 11 2 ;12(21):21147-21160. Epub 2020 Nov 2. PMID: 33136553
Article Published Date : Jan 01, 2020
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Myasthenia Gravis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Panax notoginseng saponin controls IL-17 expression in helper T cells.Dec 31, 2016

Pubmed Data : J Ocul Pharmacol Ther. 2017 05 ;33(4):285-289. Epub 2017 Jan 4. PMID: 28051353
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Panax Notoginseng
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory: Th17 downregulation
[+]

Parthenolide ameliorates colon inflammation through regulating Treg/Th17 balance in a gut microbiota-dependent manner.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Theranostics. 2020 ;10(12):5225-5241. Epub 2020 Apr 6. PMID: 32373209
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Parthenolide
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory: Th17 downregulation, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Piperlongumine may act as a promising agent for therapeutic immunosuppression.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2020 ;11:1172. Epub 2020 Jun 12. PMID: 32595640
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Piperlongumine
Pharmacological Actions : Immunomodulatory: Th17 downregulation, Immunosuppressive Agents
[+]

Red wine extract disrupts Th17 lymphocyte differentiation in a colorectal cancer context.Apr 17, 2020

Pubmed Data : Mol Nutr Food Res. 2020 Apr 18:e1901286. Epub 2020 Apr 18. PMID: 32306526
Article Published Date : Apr 17, 2020
Study Type : In Vitro Study
Additional Links
Substances : Red Wine Extract
Diseases : Colorectal Cancer
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Resveratrol has immunomodulatory activity that may be useful for autoimmune conditions such as MS. Mar 01, 2011

Pubmed Data : Int Immunopharmacol. 2011 Mar;11(3):310-8. Epub 2010 Aug 12. PMID: 20708723
Article Published Date : Mar 01, 2011
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Autoimmune Diseases, Multiple Sclerosis
Pharmacological Actions : Immunomodulatory: Th17 downregulation, Immunosuppressive Agents
[+]

Tangeretin attenuates lipopolysaccharide-induced acute lung injury.Oct 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Microb Pathog. 2019 Oct 29:103826. Epub 2019 Oct 29. PMID: 31676364
Article Published Date : Oct 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Tangeretin
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Lung Inflammation
Pharmacological Actions : Immunomodulatory: Th17 downregulation, Interleukin-22 Downregulation
[+]

Th17 cells as potential probiotic therapeutic targets in Inflammatory bowel diseases.Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2015 Sep 1 ;16(9):20841-58. Epub 2015 Sep 1. PMID: 26340622
Article Published Date : Aug 31, 2015
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Autoimmune Diseases, Inflammatory Bowel Diseases
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

The observations suggest that punicalagin exerts a protective role in Ankylosing spondylitis.Dec 31, 2019

Pubmed Data : Biomed Res Int. 2020 ;2020:4918239. Epub 2020 Sep 23. PMID: 33029510
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Punicalagin
Diseases : Spondylitis: Ankylosing
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Immunomodulatory: Th17 downregulation, NF-kappaB Inhibitor
[+]

This study explains the beneficial role of CBD in pathological memory T cells and in autoimmune diseases.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2016 ;13(1):136. Epub 2016 Jun 3. PMID: 27256343
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Cannabidiol
Diseases : Autoimmune Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Immunomodulatory, Immunomodulatory: Th17 downregulation, Nrf2 activation
[+]

This study identified that arctigenin is a selective ERβ agonist.Dec 19, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2016 Dec 20 ;7(51):83893-83906. PMID: 27863380
Article Published Date : Dec 19, 2016
Study Type : In Vitro Study
Additional Links
Substances : Arctigenin
Diseases : Colitis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Thymol as a reciprocal regulator of T cell differentiation: Promotion of regulatory T cells and suppression of Th1/Th17 cells.Jan 31, 2019

Pubmed Data : Int Immunopharmacol. 2019 Feb ;67:417-426. Epub 2018 Dec 31. PMID: 30586665
Article Published Date : Jan 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Thymol
Diseases : Immune Dysregulation: TH17 over-expression, Immune Dysregulation: TH1 dominance
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Total glucosides of paeony ameliorates TNBS‑induced colitis by modulating differentiation of Th17/Treg cells and the secretion of cytokines.Nov 30, 2017

Pubmed Data : Mol Med Rep. 2017 Dec ;16(6):8265-8276. Epub 2017 Sep 25. PMID: 28944916
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Peony
Diseases : Colitis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Urolithin A ameliorates experimental autoimmune encephalomyelitis by targeting aryl hydrocarbon receptor.Jan 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : EBioMedicine. 2021 Feb ;64:103227. Epub 2021 Jan 30. PMID: 33530002
Article Published Date : Jan 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Urolithin A
Diseases : Encephalomyelitis
Pharmacological Actions : Immunomodulatory, Immunomodulatory: Th17 downregulation
[+]

Z. multiflora showed anti-inflammatory, antioxidant, and immunomodulatory effects.Jan 31, 2018

Pubmed Data : Fundam Clin Pharmacol. 2018 Feb ;32(1):26-50. PMID: 29125648
Article Published Date : Jan 31, 2018
Study Type : Review
Additional Links
Substances : Zataria multiflora
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Immunomodulatory, Immunomodulatory: Th17 downregulation, Interleukin-4 downregulation
Additional Keywords : Phytotherapy, Plant Extracts

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