Abstract Title:

[Wheat dependent exercise induced anaphylaxis possibly sensitized by the hydrolyzed wheat proteins in a facial cleansing soap].

Abstract Source:

J UOEH. 2012 Mar 1 ;34(1):85-9. PMID: 22428462

Abstract Author(s):

Miwa Kobayashi, Risa Okura, Haruna Yoshioka, Kana Hiromasa, Manabu Yoshioka, Motonobu Nakamura

Article Affiliation:

Department of Dermatology, School of Medicine, University of Occupational and Environmental Health, Japan.


There are increasing cases of wheat dependent exercise-induced anaphylaxis (WDEIA) with transcutaneous or transmucosal sensitization. Hydrolyzed wheat included in a certain brand of soap was identified as a cause of sensitization. The useful clues to detect this disorder consist of the patient's past usage of a soap containing hydrolyzed wheat, the appearance of cutaneous or mucosal symptoms after the intake of wheat or washing with this soap, and a high level of specific IgE for wheat gluten. Because hydrolyzed wheat is used as an additive in a wide variety of cosmetics, we should pay careful attention to the ingredients of cosmetics when observing WDEIA.

Study Type : Review
Additional Links
Problem Substances : Wheat : CK(2781) : AC(341)
Adverse Pharmacological Actions : Immunoreactive : CK(237) : AC(54)

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