Abstract Title:

Panuveitis With Exudative Retinal Detachments After Vaccination Against Human Papilloma Virus.

Abstract Source:

Ophthalmic Surg Lasers Imaging Retina. 2015 Oct ;46(9):967-70. PMID: 26469238

Abstract Author(s):

Kunal K Dansingani, Mihoko Suzuki, Jonathan Naysan, C Michael Samson, Richard F Spaide, Yale L Fisher

Article Affiliation:

Kunal K Dansingani


A 20-year-old white woman presented with bilateral acute visual loss (visual acuity: 20/60), panuveitis, and exudative retinal detachments 3 weeks after a second dose of quadrivalent human papillomavirus (HPV4) vaccine. She was treated with oral prednisolone for 6 weeks and responded rapidly. By week 4, vision had normalized and clinical signs resolved. Uveitis after HPV4 vaccination has been reported in two cases. Although the differential diagnosis includes Harada disease, temporal correlation with HPV4 and definitive response to a short course of treatment implicate the vaccine in this case. Vaccine-induced uveitis is rare and difficult to distinguish from coincidental autoimmune disease.

Study Type : Human: Case Report

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Sayer Ji
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