Abstract Title:

Acupuncture increases the diameter and reorganisation of collagen fibrils during rat tendon healing.

Abstract Source:

Acupunct Med. 2015 Feb ;33(1):51-7. Epub 2014 Aug 19. PMID: 25138672

Abstract Author(s):

Marcos dos Santos de Almeida, Karine Moura de Freitas, Letícia Prado Oliveira, Cristiano Pedrozo Vieira, Flávia Da Ré Guerra, Mary Anne Heidi Dolder, Edson Rosa Pimentel

Article Affiliation:

Marcos dos Santos de Almeida


BACKGROUND: Our previous study showed that electroacupuncture (EA) increases the concentration and reorganisation of collagen in a rat model of tendon healing. However, the ultrastructure of collagen fibrils after acupuncture is unknown.

OBJECTIVES: To assess the effect of acupuncture protocols on the ultrastructure of collagen fibrils during tendon healing.

METHODS: Sixty-four rats were divided into the following groups: non-tenotomised (normal group), tenotomised (teno group), tenotomised and subjected to manual acupuncture at ST36 (ST36 group), BL57 (BL57 group) and ST36+BL57 (SB group) and EA at ST36+BL57 (EA group). The mass-average diameter (MAD) and the reorganisation of collagen fibril diameters were determined during the three phases of tendon healing (at 7, 14 and 21 days).

RESULTS: The MAD increased during the three phases of healing in the SB group. In the EA group, MAD increased initially but was reduced at day 21. The reorganisation of collagen fibrils was improved in the EA and SB groups at days 14 and 21, respectively. EA at day 21 appeared to reduce the reorganisation.

CONCLUSIONS: These results indicate that the use of EA up to day 14 and manual acupuncture at ST36+BL57 up to day 21 improve the ultrastructure of collagen fibrils, indicating strengthening of the tendon structure. These data suggest a potential role for acupuncture in rehabilitation protocols.

Study Type : Animal Study

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