Article Publish Status: FREE
Abstract Title:

Maternal Exposure to Bisphenol A Impacts on Fecundity in F1 and F2 Generations in.

Abstract Source:

Dev Reprod. 2021 Sep ;25(3):193-197. Epub 2021 Sep 30. PMID: 34950822

Abstract Author(s):

Sohee Kim, Kyong-Hwa Kang, Hyongjong Koh

Article Affiliation:

Sohee Kim


In previous reports, bisphenol A (BPA) exposure affects reproductive function infemales. To test the maternal effect of BPA exposure on fly reproductive function, F0 mothers were exposed to 0, 0.1, 1, and 10 mg/L of BPA and the fecundity in F1 and F2 generations were checked. In this experiment, 1 and 10 mg/L BPA significantly decreased the fecundity of F1 females. Moreover, 0.1 and 1 mg/L BPA substantially reduced egg production in the F2 generation. These results suggested that maternal exposure to BPA at enviromentally relavant concnetrations reduces reproductive function infemales and that this effect is transgenerational.

Study Type : In Vitro Study
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Additional Keywords : Transgenerational inheritance

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