Article Publish Status: FREE
Abstract Title:

A Microencapsulated Mixture of Eugenol and Garlic Tincture Supplementation Mitigates the Effect of Necrotic Enteritis on Intestinal Integrity and Increases Goblet Cells in Broilers.

Abstract Source:

Microorganisms. 2021 Jul 6 ;9(7). Epub 2021 Jul 6. PMID: 34361887

Abstract Author(s):

Alip Kumar, Sarbast K Kheravii, Catherine Ionescu, Alexandra Blanchard, Reza Barekatain, Yadav S Bajagai, Shu-Biao Wu

Article Affiliation:

Alip Kumar


This study was conducted to examine the effects of a plant extract mixture, a microencapsulated product composed of eugenol and garlic tincture (PE), on intestinal health in broilers under necrotic enteritis (NE) challenge. A total of 960 d-old mixed-sex Cobb 500 chicks were randomly distributed to 48-floor pens housing 20 birds per pen. Six treatments were applied: UC, unchallenged control; CC, challenged control; PE, challenged group plus PE; AM, challenged group plus antimicrobial (AM); FAP, challenged group plus a full dose of AM with PE; HAP, challenged group plus a half dose of AM with PE in starter, grower and finisher phases. Birds in the challenged groups were inoculated withspp. on d 9 andon d 14. On d 16, the CC group had increased serum fluorescein isothiocyanate dextran (FITC-d), reduced villus surface area, goblet cell number, upregulated,genes and reduced microbial diversity compared to the UC group (<0.05). Birds fed PE had reduced FITC-d, increased goblet cell number andcompared to the CC group (<0.05). Birds fed PE had reducedexpression in male birds, andspp. in female birds than CC group (<0.05). These findings suggest that PE supplementation mitigates the effect of NE by improving the intestinal health of birds.

Study Type : Animal Study

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