Article Publish Status: FREE
Abstract Title:

Therapeutic potential of silymarin as a natural iron-chelating agent inβ-thalassemia intermedia.

Abstract Source:

Clin Case Rep. 2022 Jan ;10(1):e05293. Epub 2022 Jan 24. PMID: 35106163

Abstract Author(s):

Nahid Reisi, Nafiseh Esmaeil, Marjan Gharagozloo, Behjat Moayedi

Article Affiliation:

Nahid Reisi


Abnormal iron accumulation in vital organs is one of the major complications ofβ-thalassemia intermedia (β-TI). Silymarin, a flavonolignan isolated from, significantly decreases the serum ferritin levels ofβ-TI patients. This finding suggests silymarin as a safe and effective natural iron-chelating agent for the treatment of iron-overloaded conditions.

Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Iron Chelating Agents : CK(40) : AC(15)

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