Abstract Title:

Synergistic activity ofandessential oils against.

Abstract Source:

Nat Prod Res. 2020 Aug 25:1-5. Epub 2020 Aug 25. PMID: 32840389

Abstract Author(s):

Letizia Angiolella

Article Affiliation:

Letizia Angiolella


The antifungal activity ofessential oil (PCEO) andessential oil (CMEO) againstwere evaluated. The main components of essential oils wereβ-cytronellol 58.81% and geraniol 83.94% in PCEO and CMEO, respectively. PCEO was more activity than CMEO for allstrains tested with values MICor MICof 780 µg/ml. PCEO used in combination with fluconazole or CMEO shows synergistic effect with FICI values ≤ 0.5. Moreover both essential oils are able to inhibit the major virulence factor ofas the germ tube formation at sub-inhibitory concentration of 195 µg/ml. In conclusion, it is possible to hypothesize that PCEO can be used in combination with fluconazole or CMEO. Further studies are in due course to confirm these results.

Study Type : In Vitro Study

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