Abstract Title:

Effects of placentophagy on serum prolactin and progesterone concentrations in rats after parturition or superovulation.

Abstract Source:

J Reprod Fertil. 1980 Nov ;60(2):273-8. PMID: 7431335

Abstract Author(s):

M S Blank, H G Friesen

Abstract:

In rats that were allowed to eat the placentae after parturition concentrations of serum prolactin were elevated on Day 1 but concentrations of serum progesterone were depressed on Days 6 and 8 post partum when compared to those of rats prevented from eating the placentae. In rats treated with PMSG to induce superovulation serum prolactin and progesterone values were significantly (P<0.05) elevated on Days 3 and 5 respectively, after being fed 2 g rat placenta/day for 2 days. However, feeding each rat 4 g placenta/day significantly (P<0.02) lowered serum progesterone on Day 5. Oestrogen injections or bovine or human placenta in the diet had no effect. The organic phase of a petroleum ether extract of rat placenta (2 g-equivalents/day) lowered peripheral concentrations of progesterone on Day 5, but other extracts were ineffective. We conclude that the rat placenta contains orally-active substance(s) which modify blood levels of pituitary and ovarian hormones.

Study Type : Animal Study
Additional Links
Therapeutic Actions : Placentophagy : CK(9) : AC(6)

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