Abstract Title:

[Antimicrobial activity of Morinda morindoides on in vitro growth of vibrio cholerae in Côte d'Ivoire].

Abstract Source:

J Med Food. 2004 Summer;7(2):168-79. PMID: 20337116

Abstract Author(s):

A E Koffi, H F Yapi, C Bahi, K N Guessend, J A Djaman, F Guede-Guina

Article Affiliation:

Laboratoire de Microbiologie, Institut National de Santé Publique (INSP), Abidjan, Côte d'Ivoire. koffiallali@yahoo.fr


Cholera is a major public health problem in developing countries. As a contribution to management of this disease, the study described herein was carried out in Côte d'Ivoire. The purpose was to evaluate the antibacterial activity of products obtained by various techniques from the leaves of Morinda morindoides on a pathogenic strain of Vibrio cholerae O:1. Morinda morindoides is a medicinal plant in the Ivorian pharmacopoeia. The products were obtained asaqueous extracts, 70% ethanolic extracts, residual extracts and a chromatographic fraction (BGG F5). All three extracts and the chromatographic fraction showed considerable in vitro antimicrobial efficacy against Vibrio cholerae O:1. The most active against in vitro growth of Vibrio cholorae O:1 wasthe 70% ethanolic extract with a minimal bactericidal concentration of 5 mg/ml. The antibacterial properties of this medicinal plant can be of great benefit for management of cholera.

Study Type : In Vitro Study

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