Article Publish Status: FREE
Abstract Title:

Multisystem Inflammatory Syndrome in a Previously Vaccinated Adolescent Female With Sickle Cell Disease.

Abstract Source:

Pediatr Infect Dis J. 2022 03 1 ;41(3):e104-e105. PMID: 34955521

Abstract Author(s):

Joshua DeJong, Rebecca Sainato, Melissa Forouhar, David Robinson, Anjali Kunz

Article Affiliation:

Joshua DeJong


Multisystem inflammatory syndrome in children (MIS-C) is a serious complication that is observed most commonly in pediatric patients following severe acute respiratory syndrome coronavirus 2 infections. However, the mechanism and predictors of disease are poorly understood. There are no prior reports of MIS-C among patients who have been fully vaccinated, and only a single case of MIS in an adult patient who had received his second shot just 4 days prior to symptom onset. Here, we present an adolescent with sickle cell disease who was fully vaccinated against severe acute respiratory syndrome coronavirus 2 and had no prior history of known or suspected infection, who presented in shock and was ultimately diagnosed with MIS-C. This case highlights the importance of clinical suspicion for MIS-C even when patients are fully vaccinated.

Study Type : Human: Case Report

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