Article Publish Status: FREE
Abstract Title:

Effectiveness of personal protective measures in reducing pandemic influenza transmission: A systematic review and meta-analysis.

Abstract Source:

Epidemics. 2017 09 ;20:1-20. Epub 2017 Apr 30. PMID: 28487207

Abstract Author(s):

Patrick Saunders-Hastings, James A G Crispo, Lindsey Sikora, Daniel Krewski

Article Affiliation:

Patrick Saunders-Hastings


The goal of this review was to examine the effectiveness of personal protective measures in preventing pandemic influenza transmission in human populations. We collected primary studies from Medline, Embase, PubMed, Cochrane Library, CINAHL and grey literature. Where appropriate, random effects meta-analyses were conducted using inverse variance statistical calculations. Meta-analyses suggest that regular hand hygiene provided a significant protective effect (OR=0.62; 95% CI 0.52-0.73; I=0%), and facemask use provided a non-significant protective effect (OR=0.53; 95% CI 0.16-1.71; I=48%) against 2009 pandemic influenza infection. These interventions may therefore be effective at limiting transmission during future pandemics. PROSPERO Registration: 42016039896.

Study Type : Meta Analysis, Review

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Sayer Ji
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