Abstract Title:

Long-term Amelioration of OCD Symptoms in a Patient with Chronic Consumption of Psilocybin-containing Mushrooms.

Abstract Source:

J Psychoactive Drugs. 2021 Apr-Jun;53(2):146-148. Epub 2020 Nov 22. PMID: 33225874

Abstract Author(s):

Agustin Lugo-Radillo, Jorge Luis Cortes-Lopez

Article Affiliation:

Agustin Lugo-Radillo


Obsessive Compulsive Disorder (OCD) is a chronic neuropsychiatric condition, characterized by obsessions and compulsions, which is usually disabling for the suffering individual. The first-line treatment is not effective in all patients. There is evidence showing the effectiveness of psilocybin and psilocybin-containing mushrooms in the treatment of OCD symptoms. We present the case of a male adult with OCD who showed a clinically meaningful reduction of his OCD symptomatology after the consumption of psilocybin-containing mushrooms. Future research will determine if psilocybin and other psychoactive compounds of psilocybin-containing mushrooms are effective and safe for the treatment of OCD.

Study Type : Human: Case Report

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