Abstract Title:

COVID-19 Vaccine-Induced Multisystem Inflammatory Syndrome With Polyserositis Detected by FDG PET/CT.

Abstract Source:

Clin Nucl Med. 2022 Feb 16. Epub 2022 Feb 16. PMID: 35175945

Abstract Author(s):

Soo Jin Lee, Dong Won Park, Jang Won Sohn, Ho Joo Yoon, Sang-Heon Kim

Article Affiliation:

Soo Jin Lee


Of the various adverse reactions to COVID-19 vaccines, fever is a common systemic symptom that often resolves spontaneously without treatment. However, rare vaccine-induced conditions that present with fever and systemic inflammation have been reported. In this case, a 65-year-old man with BNT162b2 mRNA COVID-19 vaccination underwent 18F-FDG PET/CT to evaluate prolonged fever and elevated serum C-reactive protein. PET/CT showed hypermetabolic infiltration in the pericardium and peritoneum suggesting immune-mediated pericarditis and peritonitis. After administration of high-dose corticosteroids, the patient's symptom resolved. This case suggests that multisystem inflammatory syndrome and polyserositis can be induced by the COVID-19 vaccine.

Study Type : Human: Case Report
Additional Links
Anti Therapeutic Actions : Vaccination: COVID-19 : CK(3) : AC(1)
Adverse Pharmacological Actions : Inflammatory : CK(423) : AC(132)

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