Abstract Title:

Anti-HIV coumarins from Calophyllum seed oil.

Abstract Source:

Bioorg Med Chem Lett. 1998 Dec 15;8(24):3475-8. PMID: 9934455

Abstract Author(s):

C Spino, M Dodier, S Sotheeswaran

Article Affiliation:

Université de Sherbrooke, Département de Chimie, Qc., Canada.


The seeds of Calophyllum cerasiferum Vesque (Family-Clusiaceae), and Calophyllum inophyllum Linn. (Family-Clusiaceae) contain several known coumarins, among which were the potent HIV reverse transcriptase inhibitors costatolide and inophyllum P. Calophyllum cerasiferum contained (-)-calanolide B as its major coumarin constituent in significant amount and thus constitute a renewable source of this compound.

Study Type : In Vitro Study

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