Article Publish Status: FREE
Abstract Title:

Bioaccessibility and Antioxidant Activity of Calendula officinalis Supercritical Extract as Affected by in Vitro Codigestion with Olive Oil.

Abstract Source:

J Agric Food Chem. 2016 Nov 23 ;64(46):8828-8837. Epub 2016 Nov 8. PMID: 27796089

Abstract Author(s):

Diana Martin, Joaquín Navarro Del Hierro, David Villanueva Bermejo, Ramón Fernández-Ruiz, Tiziana Fornari, Guillermo Reglero

Article Affiliation:

Diana Martin


Supercritical extracts of marigold (ME) were produced and characterized. The bioaccessibility of terpenes, especially that of pentacyclic triterpenes (PT), the particle-size distribution, and antioxidant activity after the in vitro codigestion of ME with olive oil (OO) were determined. ME produced without cosolvent was richer in taraxasterol, lupeol,α-amyrin, and β-amyrin than extracts with cosolvent. All terpenes showed high bioaccessibility without OO (>75%). Significant correlations were found between the molecular properties of compounds (logP and number of rotatable bonds) and their bioaccessibility. Codigestion with OO enhanced the bioaccessibility (around 100% for PT), which could be related to a higher abundance of low-size particles of the digestion medium. The antioxidant activity of the digested ME increased around 50%, regardless of OO. PT-rich extracts from marigold display high bioaccessibility and improved antioxidant activity after in vitro digestion, although complete bioaccessibility of PT can be reached by codigestion with oil, without affecting antioxidant activity.

Study Type : In Vitro Study

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