Article Publish Status: FREE
Abstract Title:

Assessment of the Cytotoxic Activity of Triphala: A Semisolid Traditional Formulation on HepGCancer Cell Line.

Abstract Source:

Biomed Res Int. 2021 ;2021:6689568. Epub 2021 Aug 11. PMID: 34471640

Abstract Author(s):

Ali Sahragard, Zohreh Alavi, Zohreh Abolhassanzadeh, Mahmoodreza Moein, Afshin Mohammadi-Bardbori, Mahmoud Omidi, Mohammad M Zarshenas

Article Affiliation:

Ali Sahragard


Cancer chemotherapies may result in resistance, and therefore, contemporary treatments including natural products may find an increasing consideration. As per Persian medicine (PM), many natural products have been used for malignant and chronic diseases. Triphala, with a combination ofRetz.,Retz.,L., and honey, is a multi-ingredient traditional formulation attributed to anticancer activities in PM. This study is aimed at evaluating the cytotoxic activity of this preparation on HepG, the human liver cancer cell line. Hydroalcoholic extracts were prepared from the formulation and its components. Compared with the control and Cisplatin, the extracts were tested using MTT assay at different concentrations. All concentrations of the preparation, as well as Cisplatin, were effective significantly against HepGcells. All extract preparations at multiple concentrations were significantly effective as evidenced by MTT assay when compared to the control group. The IClevel for Triphala extract was 77.63± 4.3 g/ml. Based on the results, Triphala and its components have cytotoxic activity on the HepGcancer cell line and they can reduce the survival rate significantly.

Study Type : In Vitro Study

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2022 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.