Abstract Title:

Oxidants/antioxidants in idiopathic pulmonary fibrosis.

Abstract Source:

Thorax. 1995 Sep;50 Suppl 1:S53-8. PMID: 7570466

Abstract Author(s):

W MacNee, I Rahman


Six hundred mg of N-acetylcysteine 3 times a day by mouth for 5 days in 17 nonsmoking patients with idiopathic pulmonary fibrosis showed a significant increase in glutathione levels in the bronchoalveolar lavage fluid, as compared to pretreatment showing that N-acetylcysteine therapy can augment deficient lung glutathione levels in patients with idiopathic pulmonary fibrosis, therefore, enhancing pulmonary antioxidant protection.

Study Type : Human Study

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